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| 12.04.2025 | D1 | Hoffenheim | 2-0 | Mainz 05 | |
| 01.12.2024 | D1 | Mainz 05 | 2-0 | Hoffenheim | |
| 13.04.2024 | D1 | Mainz 05 | 4-1 | Hoffenheim | |
| 26.11.2023 | D1 | Hoffenheim | 1-1 | Mainz 05 | |
| 04.03.2023 | D1 | Mainz 05 | 1-0 | Hoffenheim | |
| 14.01.2023 | CF | Mainz 05 | 2-2 | Hoffenheim |
| GP | W | D | L | GF | GA | +/- | |
| home | 6 | 2 | 1 | 3 | 7 | 10 | -3 |
| away | 6 | 2 | 1 | 3 | 8 | 10 | -2 |
| total | 6 | 2 | 1 | 3 | 8 | 10 | -2 |
| Mainz 05 win | 40.54% | 15 |
| draw | 27.03% | 10 |
| Mainz 05 lose | 32.43% | 12 |
| GP | W | D | L | GF | GA | +/- | |
| home | 6 | 3 | 0 | 3 | 16 | 10 | 6 |
| away | 6 | 4 | 2 | 0 | 15 | 8 | 7 |
| total | 6 | 3 | 2 | 1 | 12 | 7 | 5 |
| Hoffenheim win | 32.43% | 12 |
| draw | 27.03% | 10 |
| Hoffenheim lose | 40.54% | 15 |
| 06.11.2025 | ECL | Mainz 05 | 2-1 | Fiorentina |  |
| 01.11.2025 | D1 | Mainz 05 | 1-1 | Werder Bremen |  |
| 29.10.2025 | Cup | Mainz 05 | 0-2 | VfB Stuttgart |  |
| 26.10.2025 | D1 | VfB Stuttgart | 2-1 | Mainz 05 | |
| 23.10.2025 | ECL | Mainz 05 | 1-0 | Zrinjski Mostar | |
| 18.10.2025 | D1 | Mainz 05 | 3-4 | Bayer Leverkusen | |
| 02.11.2025 | D1 | VfL Wolfsburg | 2-3 | Hoffenheim | |
| 28.10.2025 | Cup | St. Pauli | 2-2/p.8-7 | Hoffenheim | |
| 25.10.2025 | D1 | Hoffenheim | 3-1 | 1. FC Heidenheim | |
| 19.10.2025 | D1 | St. Pauli | 0-3 | Hoffenheim | |
| 03.10.2025 | D1 | Hoffenheim | 0-1 | 1.FC Köln | |
| 28.09.2025 | D1 | SC Freiburg | 1-1 | Hoffenheim | |
| over 2.5 | 50.00% | 11 |
| under 2.5 | 50.00% | 11 |
| over 2.5 | 80.00% | 16 |
| under 2.5 | 20.00% | 4 |
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